(especially versions 6.1.x and newer) relies on the Visual C++ runtime for several core components:
If you’re trying to run on Windows and getting hit with "Missing Dependency" errors, installing the Microsoft Visual C++ 2019 Redistributable is the ultimate "fix-it" button. c++ 2019 redistributable virtualbox
If you’re having issues, install it manually first, then reinstall VirtualBox. (especially versions 6