Cosmid Instant

| Start | End | Feature Name | Description | | :--- | :--- | :--- | :--- | | 1 | 12 | | Lambda phage cohesive end site ($\cos L$); required for packaging DNA into phage particles. | | 250 | 1,100 | ori | Origin of replication (ColE1); allows the vector to replicate as a plasmid inside the bacterial host. | | 1,500 | 2,361 | AmpR | Beta-lactamase gene conferring resistance to ampicillin; used for selecting transformed bacteria. | | 2,400 | 2,800 | MCS | Multiple Cloning Site; contains unique restriction sites (e.g., BamHI, EcoRI, HindIII) for DNA insertion. | | 3,500 | 3,512 | cos site | Second lambda phage cohesive end site ($\cos R$); pairs with the first site to form the circular packaging signal. |

A typical cosmid is essentially a plasmid that has been "upgraded" with a specific viral sequence: Cosmid Vector - an overview | ScienceDirect Topics cosmid

Essentially, cosmids can be thought of as plasmids that have been engineered to carry larger DNA inserts, typically up to 45 kilob... Patsnap Synapse Cosmid - Wikipedia A cosmid is a type of hybrid plasmid that contains a Lambda phage cos sequence. Often used as cloning vectors in genetic engineeri... Wikipedia Construction and Use of Cosmid Contigs However, with the advent of yeast artificial chromosome (YAC) (4), bacterial artificial chromosome (BAC) (5), and P1-derived artif... Springer Nature Experiments Cosmid Library Construction and Functional Cloning - PubMed Abstract. Cosmid libraries can represent an entire genome in a library of circular DNA molecules, allowing for the faithful amplif... National Institutes of Health (.gov) Cosmid vector Oct 25, 2013 — | Start | End | Feature Name |