CTN’s high 5‑HT₂A affinity, combined with D₂ partial agonism, mirrors the pharmacology of atypical antipsychotics but without appreciable α‑adrenergic or histaminergic activity.
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CTN readily crosses the blood‑brain barrier, achieving brain concentrations ~ 2‑fold higher than plasma at C max . CTN’s high 5‑HT₂A affinity, combined with D₂ partial