Kaplan Question A — Day

This patient has (elevated BUN, Cr, low urine output) with hyperkalemia and edema. The most likely mechanism for hyperkalemia in CKD is reduced aldosterone activity — either due to low renin (hyporeninemic hypoaldosteronism, common in diabetic nephropathy or hypertensive nephrosclerosis) or reduced functional renal mass impairing potassium secretion.

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